Job Opportunities
Post Doctoral Fellow
Rupa Sridharan Lab
A postdoctoral position is available in the Sridharan laboratory, Epigenetics theme-Wisconsin Institute of Discovery and Dept of Cell and Regenerative Biology, to determine chromatin roadblocks to somatic cell reprogramming. Highly motivated recent Ph.D graduates who want to develop an independent research career are desired. Experience in standard molecular biology and biochemistry or genomics techniques is required. If interested, please email your cover letter stating career goals, CV with contact information of three references and first-authored publications. More information at http://www.crb.wisc.edu/faculty/sridharan.asp
Post Doctoral Fellow
Weibo Cai Lab
A Post-Doctoral position is currently available in the Cai group at the University of Wisconsin - Madison, which focuses on molecular imaging and nanotechnology. A PhD or MD/PhD degree in molecular biology, biochemistry, cell biology, or related biomedical fields is required. Good written and oral communication skills, self-motivation, ability to work independently or in a team-oriented setting in a multidisciplinary environment are required.
Experience in protein engineering, gene transfection, stem cells, protein expression, molecular biology, and histology are highly desirable. Research topics include molecular imaging, stem cell research, nanotechnology/nanomedicine, cancer research, among others. This position is renewable on an annual basis. Salary will be determined based on the experience of the candidate and the University guidelines for Postdoctoral Fellows.
To apply, please submit your current CV to Prof. Weibo Cai by e-mail: wcai@uwhealth.org.
Post Doctoral Fellow
Joyce Teng Lab
The Teng laboratory in the department of Dermatology is recruiting a NIAMS/NIH funded T32 post-doctoral candidate to take part in an integrated translational research with specific focus on cutaneous genetic disorders. The project involves broad interaction with other investigators in the field of medicine, biomedical science and tissue engineering. The main goal of this project is to further the development of disease, patient-specific induced pluripotent stem cells (iPSC) and in vitro models to study cutaneous diseases that will lead to drug discovery and autologous patient-specific cellular therapies using iPS cells. The candidate should have an M.D., Ph.D., M.D./Ph.D., and must be a US citizen or permanent resident.
Interested candidates should email their CV and statement of interest to: jteng@dermatology.wisc.edu
Post Doctoral Fellow: Department of Surgery
Bo Liu Lab
Two NIH funded postdoctoral positions are available in the Vascular Surgery Research Laboratories of Drs. K. Craig Kent and Bo Liu to investigate the molecular and cellular mechanisms of vascular diseases including restenosis and abdominal aortic aneurysm. Research topics include signaling transduction, cell proliferation and migration, cell apoptosis and vascular inflammation. PhD or M.D./PhD in molecular biology, biochemistry or cell biology or related biomedical fields are required. Experiences in transgenic mice, animal modeling and immunohistology are desired. The incumbent will join a group of physicians and scientists who emphasizes multidisciplinary and collaborative approaches to address fundamental questions underlying human diseases. Duties will include designing and conducting experiments, participating in preparation of research manuscripts and grants, and contributing to other team efforts related to research projects.
Please send curriculum vitae to: Bo Liu, PhD, liub@surgery.wisc.edu
Post Doctoral Fellow
Emery Bresnick Cell & Regenerative Biology web page
Emery Bresnick Molecular & Cellular Pharmacology Graduate Training Program web page
The Bresnick laboratory is recruiting one or two postdoctoral fellows to join our research group at the Wisconsin Institutes For Medical Research (WIMR) in the University of Wisconsin School of Medicine and Public Health. The WIMR provides a cutting-edge scholarly environment for conducting innovative basic and translational research.
We use multidisciplinary approaches to understand important biological processes, including stem/progenitor cell function, blood cell development, and vascular biology. Such approaches include genomics, proteomics, chemical genetics, and computational analysis, as well as traditional molecular, cellular, and biochemical methodologies. In addition to elucidating biological principles, we aim to develop innovative therapeutic strategies based on targeting novel mechanisms. Projects include: (1) Mechanisms of hematopoiesis. Defining such mechanisms has enormous importance, as deviations from hematopoietic programs yield leukemias, lymphomas and other blood disorders. We are analyzing the function and regulation of GATA transcription factors that control hematopoietic stem and progenitor cell function, hematopoiesis, and additional important processes. Transcriptional profiling and chromatin immunoprecipitation studies have identified a large cohort of novel GATA factor target g enes, including genes encoding proteins that bear no obvious similarity to known proteins. Loss-of-function and gain-of-function studies are being conducted in mice, zebrafish, and cultured cells to elucidate new biological pathways, which will provide key insights into mechanisms of development, differentiation, and human disease. (2) Transcriptional control of hemoglobin synthesis. These studies address fundamental mechanistic questions on how chromatin modification/remodeling regulates transcription of endogenous loci and also how hemoglobin synthesis is dysregulated in human hemoglobinopathies. Many questions remain unanswered regarding how dynamic changes in chromatin are orchestrated during development, differentiation, and pathophysiological processes. (3) Linking GATA factor mechanisms to human disease. GATA-1 mutations cause human leukemias, while GATA-2 mutations occur in leukemia as well as coronary artery disease. We discovered a link between GATA-2 function and P arkinson’s disease and also a GATA-1-regulated endogenous suppressor of angiogenesis that functions via a novel mechanism. Studying GATA factors can yield important insights of considerable relevance to human disease.
The successful candidate will develop both independent and collaborative experiments in one or more of our focal areas.
Please apply to ehbresni@wisc.edu with your cv, and comments about potential areas of interest.
Post Doctoral Fellows
Jamie Thomson Lab
The Thomson laboratory is looking for post doctoral fellows with strong backgrounds in developmental and molecular biology to pursue projects exploring human ES cell self-renewal, the basic biology of pluripotency, and reprogramming. Previous experience with homologous recombination in embryonic stem cells and BAC recombineering highly desirable.
Interested candidates should e-mail their current CV to: Dr. James Thomson
Post Doctoral Fellows
Su-Chun Zhang Lab
NIH funded openings available to study (1) epigenetic regulation of neuroectodermal specification and (2) functional implication of human neural cells in neurological disorders. PhD background in developmental biology or neurodegeneration is required. Experiences in protein chemistry, bioinformatics, molecular biology, electrophysiology/imaging, or small animal microsurgery are highly desirable. The Zhang laboratory focuses on the regulation of neuroectodermal specification, neuron-glial switch, modeling of neurodegeneration, and functional implication of stem cell derivatives in neurological animal models (Zhang Lab Website).
Interested candidates should e-mail their current CV to: Dr. Su-Chun Zhang