The Alam Laboratory
Faculty > Ben K. Graf
Ben K. Graf
Professor, Orthopedics and Rehabilitation
Organ System/Disease Focus: Musculoskeletal
Aligned Research Focus: Primary interest has been in factors affecting ligament and ligament to bone healing. Have also collaborated on projects related to bone and tendon scaffolds and tissue
Research Description
Dr. Graf is a clinical collaborator on several projects relating to tissue engineering and modulation of soft tissue healing. Examples include the creation of scaffolds to promote bone healing of critical sized defects and the use of biologically active implants (sutures and screws) to deliver growth factors to healing tissues. The use of MSC’s to further modulate healing is another area of interest.
Selected References
Lu Y, Markel M, Wynn S, Nemke B, Graf BK. Comparison of Single- versus Double-Tunnel Tendon-to-Bone Healing in an Ovine Model: A Biomechanical and Histological Analysis. Am J Sports Med 2009; 37 (3): 512-517.
Lu Y, Markel MD, Nemke B, Lee J-S, Graf BK, Murphy WL. Influence of Hydroxyapatite-Coated and Growth Factor-Releasing Interference Screws on Tendon-Bone Healing in an Ovine Model. Arthroscopy: J Arthroscopic Rel Surg 2009; 25 (12) 1427-1434.
Lu Y, Lee Jae Sung, Nemke B, Baer G, Graf B, Murphy W, Markel M. Histologic evaluation fo suture material loaded with basic fibroblast growth factor (bFGF) on acute rotator cuff repair in an ovine model. Current Orthopaedic Practice 2011, vol 22, 5, p 425-431